Sophia Garabedian had been dealing with a persistent fever and painful headache when her parents found her unresponsive in her bed one morning last fall.
Doctors ultimately diagnosed the then-5-year-old Sudbury, Massachusetts, resident with eastern equine encephalitis, a rare but severe mosquito-borne virus that causes brain swelling.
Garabedian survived the potentially fatal virus after about a month in Boston hospitals, but her parents say her ordeal and ongoing recovery should be a warning as people take advantage of the outdoors this summer.
“It's been a rough year,” said David Garabedian, her father. “With any brain injury, it's hard to tell. The damage is there. How she works through it is anyone's guess.”
As the coronavirus pandemic subsides for now in the hard-hit Northeast, public health officials in the region are warning about another potentially bad summer for EEE and other insect-borne illnesses.
EEE saw an unexpected resurgence last summer across 10 states: Alabama, Connecticut, Georgia, Indiana, Massachusetts, Michigan, New Jersey, North Carolina, Rhode Island and Tennessee.
There were 38 human cases and 15 deaths from the virus, with many of the cases in Massachusetts and Michigan, according to the Centers for Disease Control and Prevention. Most years, the country sees just half a dozen cases of the virus in humans, the agency said.
In Massachusetts and New Jersey, officials have already detected EEE in mosquitoes this year, the earliest on record in those states. There have been no human or animal cases yet.
“It's unnerving,” said Scott Crans, who heads up mosquito control efforts for the New Jersey Department of Environmental Protection. “It could signal a busy year.”
Crans and other state health officials say EEE, which has no cure in humans, tends to come in two- to three-year cycles, but they also stress that mosquito borne-diseases are notoriously tricky to predict.
A relatively mild winter may have benefited mosquito populations, but below-average rainfall could have also provided a welcome counterweight, he said.
Local health officials are also warning about the risk of contracting other insect-borne illnesses as more people are spending a longer time outdoors amid the coronavirus pandemic.
In Michigan, an invasive mosquito known to transmit dengue, Zika and other tropical viruses has already been detected for the first time this season, said Mary Grace Stobierski, the state's public health veterinarian.
The state also had its first case of West Nile virus this season. A more common but less severe mosquito-borne disease than EEE, it can cause fevers, headaches, body pain and other symptoms. The infection was found in a captive hawk in early June.
Ticks are also expected to be out earlier and in larger numbers this season because of the relatively mild winter, warned Aaron Bernstein, a pediatrician at Boston Children's Hospital and a director at Harvard's School of Public Health.
That could mean more cases of debilitating Lyme disease and other tick-related illnesses for local health care systems already feeling the pressure of responding to the coronavirus, he said.
“Some of the people going into the woods more now might not be experienced with how to protect themselves in the forest, and that's a concern,” he said.
Officials say people should avoid the evening and early morning hours when mosquitoes are most active, use bug spray and wear long clothing where possible when outdoors.