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A single course of antibiotics has been shown to negatively impact infants’ microbiota

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A University of Helsinki study revealed that children receiving antibiotics have a higher number of fungal microbiota within their guts than the children in the control group, even though they were only given the course for six weeks.
These findings suggest that antibiotic therapy results in a decrease in gut bacteria, which reduces competition for space. This allows for more space for fungi and makes it easier for them to multiply. The Journal of Fungi published this study.
“Our research strongly indicates that bacteria in your gut regulates fungal microbiota. This keeps it under control. Rebecka Ventin–Holmberg, PhD student at the University of Helsinki, says that antibiotics can disrupt bacteria and allow fungi like Candida to reproduce.
The study revealed that antibiotics have long-lasting adverse effects on human health. This was a new finding.
Long-term changes in the infant’s microbiota
For infants, antibiotics are the most prescribed drug. These drugs cause major changes to the gut microbiota during infant development. These changes are also more lasting than those experienced by adults.
“Antibiotics can have adverse effects on both the bacterial and the fungal microbiota, which can result in, for example, antibiotic-associated diarrhoea,” Ventin-Holmberg says.

“In addition to antibiotics increasing the risk of developing chronic inflammation diseases such as IBD (inflammatory bowel disease), and also having a connection to overweight,” she says.
These long-term effects may be due to an imbalance of the microbiota in the gut.
Everything is connected to the gut
Recently published research involved infants infected with the respiratory syncytialvirus (RSV), who had never received antibiotics. Some children received antibiotics for complications while others did not receive any antibiotic treatment throughout the study.
Ventin -Holmberg stresses that it is crucial to study the effects of antibiotics in order to develop new techniques to prevent chronic inflammatory diseases, and other disruptions to the microbiota.
Although antibiotics have been studied in the past to affect bacterial microbiota, there are not many studies that focus on fungal microbiota. These findings suggest that fungal bacteria may play a role long-term in causing imbalance in the microbiota.
Ventin-Holmberg says that future research should be on all microorganisms in the stomach together to better understand how they interact and to get a better view of the microbiome overall.

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